Sparcl study stroke definition

Atorvastatin in stroke: a review of SPARCL and subgroup ...

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4/15/2010 · The Stroke Prevention by Aggressive Reduction of Cholesterol Levels (SPARCL) trial showed daily treatment with 80 mg of atorvastatin in patients with a recent stroke or transient ischemic attack (TIA) reduced the incidence of fatal or nonfatal stroke by 16%. Several post hoc analyses of different subgroups followed the SPARCL study.

Atorvastatin in stroke: a review of SPARCL and subgroup ...

Statin Treatment and the Occurrence of Hemorrhagic Stroke ...

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The SPARCL study enrolled 4731 patients who had a stroke or TIA within 1 to 6 months before study entry. 6 Stroke or TIA had to be diagnosed by a neurologist within 30 days after the event. In total, 2365 patients were randomized to receive 80 mg atorvastatin per …

Statin Treatment and the Occurrence of Hemorrhagic Stroke ...

The SPARCL trial: Atorvastatin reduces risk of stroke in ...

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Lastly, the study was not powered to examine the effect on mortality. Nevertheless, the SPARCL trial has been influential, and has informed the AHA/ASA recommendation for statin therapy in patients with prior stroke and TIA. In sum, statins should be considered in patients soon after a …

The SPARCL trial: Atorvastatin reduces risk of stroke in ...

SPARCL - What does SPARCL stand for? The Free Dictionary

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The SPARCL study, published in the New England Journal of Medicine in 2006, is the only study to date evaluating the benefits of a statin solely in patients with a prior stroke or mini-stroke (n=4,731).

SPARCL - What does SPARCL stand for? The Free Dictionary

SPARCL - Stroke Prevention by Aggressive Reduction in ...

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How is Stroke Prevention by Aggressive Reduction in Cholesterol Levels abbreviated? SPARCL stands for Stroke Prevention by Aggressive Reduction in Cholesterol Levels. SPARCL is defined as Stroke Prevention by Aggressive Reduction in Cholesterol Levels frequently. ... (SPARCL) study involved 4,731 people who had a recent stroke or transient ...

SPARCL - Stroke Prevention by Aggressive Reduction in ...

Secondary prevention after ischaemic stroke: the ASPIRE-S ...

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10/23/2015 · The stroke population in North Dublin has previously been characterised by the North Dublin Population Stroke Study group (NDPSS) [11, 12], which reported that over 90 % of acute stroke cases are treated in an acute hospital. For the ASPIRE-S study, hospital-based case ascertainment was performed and a representative sample of patients with IS ...

Secondary prevention after ischaemic stroke: the ASPIRE-S ...

Atherogenic Dyslipidemia and Residual Cardiovascular Risk ...

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Background and Purpose—Treatment with statins reduces the rate of cardiovascular events in high-risk patients, but residual risk persists. At least part of that risk may be attributable to atherogenic dyslipidemia characterized by low high-density lipoprotein cholesterol (≤40 …

Atherogenic Dyslipidemia and Residual Cardiovascular Risk ...

High and Moderate Intensity Statin Therapy Following ...

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Cholesterol Levels ( SPARCL) study convincingly demonstrated that intensive lipid lowering therapy using statin medication was associated with significant reduction in the rate of recurrent ischemic stroke and other major coronary events.(4) Opportunity for Improvement Patients suffering from ischemic stroke frequently have atherosclerosis of

High and Moderate Intensity Statin Therapy Following ...

Stroke Prevention and Treatment | JACC: Journal of the ...

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8/24/2010 · The decline in stroke incidence and mortality in the U.S. over the past 20 years is reaching a plateau, and the number of strokes may actually start to increase as the population ages. However, recent clinical trials have demonstrated that there are numerous opportunities to improve stroke prevention strategies and also opportunities to effectively intervene in and treat acute strokes.

Stroke Prevention and Treatment | JACC: Journal of the ...

Secondary Prevention after Ischemic Stroke or Transient ...

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Key Clinical Points Secondary Prevention After Ischemic Stroke or Transient Ischemic Attack. Patients who have had an ischemic stroke or TIA are at high risk for recurrent stroke, myocardial ...

Secondary Prevention after Ischemic Stroke or Transient ...

Economic Evaluation of Atorvastatin for Prevention of ...

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This study evaluated the economic implications of results obtained by the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) trial.

Economic Evaluation of Atorvastatin for Prevention of ...

Cryptogenic Stroke and Underlying Atrial Fibrillation | NEJM

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Study Design. The Cryptogenic Stroke and Underlying AF (CRYSTAL AF) trial was a parallel-group trial comparing the time to detection of atrial fibrillation with an ICM versus conventional follow ...

Cryptogenic Stroke and Underlying Atrial Fibrillation | NEJM

SPARCL – Stroke Prevention by Aggressive Reduction in ...

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10/29/2014 · SPARCL – Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL). Jim McMorran Coventry GP GP with Specialist Interest in Diabetes and Cardiovascular Risk Coventry PCT. Evidence Base Prior to SPARCL. Primary Prevention of …

SPARCL – Stroke Prevention by Aggressive Reduction in ...

SPARCL Stroke Prevention by Aggressive Reduction in ...

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SPARCL Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) ... Exclusions AF, other cardiac sources of embolism, SAH ... – A free PowerPoint PPT presentation (displayed as a Flash slide show) on PowerShow.com - id: 1ab27b-NGIyO

SPARCL Stroke Prevention by Aggressive Reduction in ...

Statins and Risk of Intracerebral Haemorrhage in a Stroke ...

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Statins may increase the risk of intracerebral haemorrhage (ICH) in individuals with previous stroke. It remains unclear whether this applies to individuals with no history of stroke. This study is the first to explore the statin-associated risk of ICH in stroke-free individuals while considering the timing of …

Statins and Risk of Intracerebral Haemorrhage in a Stroke ...

Secondary prevention after ischaemic stroke: the ASPIRE-S ...

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10/23/2015 · Survivors of ischaemic stroke (IS) are at high-risk for future vascular events. Comprehensive information on the adequacy of secondary prevention after IS is lacking despite the knowledge that appropriate secondary prevention improves long-term patient outcomes. ASPIRE-S (Action on Secondary Prevention Interventions and Rehabilitation in Stroke) aimed to prospectively assess secondary ...

Secondary prevention after ischaemic stroke: the ASPIRE-S ...

Recurrent Ischemic Stroke: Strategies for Prevention ...

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10/1/2017 · Recurrent strokes make up almost 25% of the nearly 800,000 strokes that occur annually in the United States. Risk factors for ischemic stroke include hypertension, diabetes mellitus ...

Recurrent Ischemic Stroke: Strategies for Prevention ...

Subacute Management of Ischemic Stroke - American Family ...

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12/15/2011 · Subacute management of ischemic stroke refers to the period from when the decision to not employ thrombolytics is made up until two weeks after the stroke occurred.

Subacute Management of Ischemic Stroke - American Family ...

Discontinuing or continuing statin following intracerebral ...

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The Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) study showed a 5-year absolute risk reduction in nonfatal and fatal stroke of 2.2% for patients taking high doses of atorvastatin . In addition, the use of statins during hospitalization for ischemic stroke has been strongly associated with improved outcomes [5,6].

Discontinuing or continuing statin following intracerebral ...

Transient ischemic attack: Omen and opportunity ...

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Download Citation on ResearchGate | On Dec 1, 2006, P. Amarenco and others published High-dose Atorvastatin After Stroke or Transient Ischemic Attack

Transient ischemic attack: Omen and opportunity ...

High-dose Atorvastatin After Stroke or Transient Ischemic ...

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- Statin therapy recommended to reduce the risk of stroke or TIA and CV events - Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) study - Stroke is clinical ASCVD - According to ACC/AHA lipids guidelines

High-dose Atorvastatin After Stroke or Transient Ischemic ...
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